Pregnyl contine un hormon cunoscut ca gonadotrofina corionica umana GCh, care apartine unui grup de medicamente denumite gonadotrofine.
hCG are injected intramuscular or subcutaneously employing insulin syringes. Considering that hCG stimulates testosterone production, estrogenic and androgenic aspect-effects could possibly be knowledgeable. However hCG utilization is commonly accompanied by some type of anti-estrogen and that could maintain estrogen degrees in Verify. Pregnyl really should be saved inside a fridge concerning 2°-8°C and when reconstituted it will eventually progressively lessen in potency and eventually drop all performance in about three-4 weeks.
Consequently: Patients with latent or overt cardiac failure, renal dysfunction, hypertension, epilepsy or migraine (or simply a record of those circumstances) should be saved beneath close professional medical supervision, due to the fact aggravation or recurrence may possibly once in a while be induced as a result of enhanced androgen creation.
In the female: Undesirable ovarian hyperstimulation syndrome. That's Attribute indications of unwanted ovarian hyperstimulation as well as the ovarian hyperstimulation syndrome are provided underneath 'Exclusive warnings and Distinctive precautions to be used'.
In the case of Pregnyl this remains accomplished to this day. Just lately new methods of recombinant DNA modification authorized for just a new synthetic products named Ovidrel. Apart from the discrepancies in manufacturing processes there are several noteworthy differences in outcomes concerning Pregnyl and Ovidrel.
Tratamentul cu GCh duce la cresterea productiei de androgeni. De aceea, in urmatoarele cazuri este necesara o stricta supraveghere medicala:
In the feminine: Human Chorionic Gonadotrophin is provided as a substitute for the endogenous mid-cycle LH surge to induce the ultimate period of follicular maturation, leading to ovulation. Human Chorionic Gonadotrophin is also specified in its place for endogenous LH through the luteal phase.
Se poate create retentie de apa si sare in tesuturi si, ocazional, cresterea sanilor. Acestea pot fi provocate de cresterea productiei de androgeni in urma tratamentului cu GCh. Daca aceste semne apar, anuntati imediat read more medicul.
Kod muškaraca se lek Pregnyl, koristi u lečenju kasnog puberteta, nespuštenih testisa ili oligospermije (nedovoljne produkcije sperme). Posavetujte se sa vašim lekarom ukoliko niste sigurni zašto primate lek Pregnyl.
The drug has to be diluted inside the ampoule using a Particular liquid which is attached towards the drug. It is necessary to inject chorionic gonadotropin intramuscularly, the drug is quickly absorbed. The period of motion is five-6 days.
Pediatric Use: Induction of androgen secretion by HCG may more info perhaps induce precocious puberty in pediatric clients handled for cryptorchidism. Therapy should here be discontinued if indications of precocious puberty happen.
in tratamentul baietilor treatment nu au ajuns la pubertate. Aceasta deoarece Pregnyl poate determina dezvoltare sexuala precoce si intarzieri in crestere;
Ovidrel Alternatively only calls for storage of under 25°C and is incredibly steady even in the reconstituted condition and can previous for effectively in excess of 30 days even at room temperature. Take treatment when managing any reconstituted peptide hormone given that the DNA chains are really fragile and simply wrecked once the vial is shaken or dropped.
From the Male: Drinking water and sodium retention is from time to time observed following read more administration of high dosages; this is regarded on account of abnormal androgen manufacturing. Treatment with Pregnyl causes greater androgen manufacturing.
Lowering Testicular Atrophy: Pregnyl might assist cut down testicular atrophy that may end up from the usage of anabolic steroids. This could help retain testicular operate as well as your own testosterone generation.
upkeep with the corpus luteum: Below selected conditions, like the procedure of corpus luteum insufficiency in Ladies, Pregnyl can be used to maintain more info progesterone generation.